| Customization: | Available |
|---|---|
| Powder: | Yes |
| Certification: | ISO 9001, HACCP |
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Glimepiride is a third-generation sulfonylureas long-acting anti-diabetes drug. The main mechanism of its hypoglycemic effect is to stimulate the secretion of by beta cells of the pancreas and partially increase the sensitivity of surrounding tissues. This product binds to receptor and dissociates faster than glyburide, and causes less severe hypoglycemia. Its mechanism is through and sulfonyl urea receptors on the surface of the pancreatic beta cells (relative molecular mass of 6.5 x 104 protein), the receptor and ATP sensitive K + (KATP) channel phase coupling, pushing the KATP channel close, cause cell membrane depolarization, makes the open voltage dependent calcium channel, Ga2 + internal flow and lead to the release, and inhibit the synthesis of liver glucose. Recent studies have shown that different sulfonylurea coal drugs have different affinities with KATP. The following order: Glenn beauty urea > tolbutamide > sulfonyl chloride propyl urea. In addition, it could be a glucose transporter factor 1, 4 caused by two kinds of protein expression is increased. Due to Glenn beauty of urea to cardiovascular KATP channels in the weaker than Glenn wave urea, gliclazide pass column pyrazine. So cardiovascular adverse reactions are also rare.
SNC was established in 2006. After years of development, Good Fortune International joined the team in 2017 to jointly provide one-stop services for global users in the research and development, production, logistics, and sales of food, medicine, nutrition and health, and sports supplements.
The company has keen market observation and judgment, provides customers with the highest quality products and services with fast and sensitive response, and provides customers with "one-stop all-round" services! Committed to supplying healthy raw materials to the world, providing the highest quality raw materials for the world's health products, sports supplements, cosmetics, pharmaceuticals and other fields.
More Than 15 Years Experience
Our products are sold worldwide, like Europe, North&South America, Asia and pacific area as well as Africa, we are aiming to establish long term cooperation with our clients.
One-Stop Service
Committed to supplying healthy raw materials to the world, providing the highest quality raw materials for the world's health products, sports supplements, cosmetics, pharmaceuticals and other fields. Customized product is also available from us.
7 DAYS 24 HOURS service
In time and clear response to customers questions. 100% guaranteed aftersales service, we are happy to provide guidance or solutions during your consumption.
Quality Assurance
Dedicated to provide high-quality materials for customers with reasonable price.
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