| Customization: | Available |
|---|---|
| CAS No.: | 103-90-2 |
| Formula: | C8h9no2 |
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Acetaminophen is an organic compound with a chemical formula of C8H9NO2. It is a metabolite in the body. It can reduce the synthesis of prostaglandins PGE1, bradykinin and histamine by inhibiting the central prostaglandin synthase in the hypothalamic body temperature regulation and release. PGE1 mainly acts on the nerve center, and its reduction will lead to a decrease in the temperature setting point of the center, and the temperature receptors on the body surface will feel relatively hot, and then cause peripheral blood vessels to dilate and sweat through nerve regulation to achieve antipyretic effect, which inhibits the central nervous system The effect of prostaglandin synthesis is similar to that of aspirin, but the anti-inflammatory effect is weaker. No effect on platelets and coagulation mechanism.
| Testing Items | Specifications | Results |
| Characters | White or almost white, crystalline powder, sparingly soluble in water, freely soluble in alcohol. | Conforms |
| Identification A: Melting point C: IR |
A: 168~172ºC C: Comparison: Paracetamol CRS |
170.2ºC Conforms |
| Related substances | ||
| Chloroacetanilide (J) | ≤10ppm | Not-detected |
| Any other impurity | ≤0.05% | 0.010% |
| Total of other impurities | ≤0.1% | 0.010% |
| Loss on drying | ≤0.5% | 0.07% |
| Residual Solvent (Acetic acid) | ≤0.5% | <0.5% |
| Sulphated ash | ≤0.1% | 0.03% |
| Assay | 99.0~101.0% (on the dried sub.) | 99.7% |
SNC was established in 2006. After years of development, Good Fortune International joined the team in 2017 to jointly provide one-stop services for global users in the research and development, production, logistics, and sales of food, medicine, nutrition and health, and sports supplements.
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