| Customization: | Available |
|---|---|
| CAS No.: | 850140-73-7 |
| Formula: | C32h33clfn5o11 |
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Description Afatinib dimaleate is a salt form of afatinib. Afatinib is a second-generation oral irreversible inhibitor of the ErbB family of tyrosine kinases.
Mechanism of Action Afatinib downregulates ErbB signaling by covalently binding to the kinase domains HER4, resulting in irreversible inhibition of tyrosine kinase autophosphorylation; it Also inhibits transphosphorylation of HER3. Afatinib Approved as Monotherapy for the Treatment of EGFR Tyrosine Kinase Inhibitor (TKI) Naïve Adults with Locally Advanced or DefinitionChEBI: Obtained by Combining Afatinib with Two Molar Equivalents of Maleic Acid maleate. For the first-line treatment of patients with metastatic non-small cell lung cancer.
| BIBW2992 DiMaleate Basic information |
| Description Mechanism of Action |
| Product Name: | BIBW2992 DiMaleate |
| Synonyms: | BIBW2992 DiMaleate;BIBW2992-MA2;Afatinib (diMaleate);Afatinib (diMaleate), BIBW2992;2-ButenaMide, N-[4-[(3-chloro-4-fluorophenyl)aMino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(diMethylaMino)-, (2E)-, (2Z)-2-butenedioate (1:2);(2E)-N-(4-[(3-chloro-4-fluorophenyl)aMino]-7-{[(3S);Afatinib double Maleate;Afatinib (BIBW2992) Dimaleate |
| CAS: | 850140-73-7 |
| MF: | C28H29ClFN5O7 |
| MW: | 602.02 |
| EINECS: | 810-416-1 |
| Product Categories: | Inhibitors;tyrosine kinase receptor inhibitor;850140-73-7 |
| Mol File: | 850140-73-7.mol |
SNC was established in 2006. After years of development, Good Fortune International joined the team in 2017 to jointly provide one-stop services for global users in the research and development, production, logistics, and sales of food, medicine, nutrition and health, and sports supplements.
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