| Customization: | Available |
|---|---|
| CAS No.: | 183319-69-9 |
| Formula: | C22h24cln3o4 |
|
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Erlotinib hydrochloride is a small molecule tyrosine kinase inhibitor that reversibly acts on the epidermal growth receptor, which is the hydrochloride salt of the molecularly targeted drug erlotinib. The U.S. Food and Drug Administration (FDA) has approved erlotinib (Tarceva) in combination with as a first-line treatment for locally advanced and metastatic pancreatic cancer. It is mainly used as the second-line or third-line treatment of locally advanced or metal silent non-small cell lung cancer (NSCLC) and the treatment of pancreatic cancer. It is used as a tyrosine inhibitor in the treatment of NSCLC. Erlotinib hydrochloride (V), a quinazoline-derived small molecule inhibitor of epidermal growth receptor (EDGFR) tyrosine kinase, was approved in November 2004 for the treatment of advanced or metastatic non-small cell lung cancer .
| Appearance | White or off-white powder | Conforms |
| Identification | ||
| a) IR | IR chromatograph Conforms to the characteristic peak of R.S. | Conforms |
| b) HPLC | The retention time of the major peak in the chromatogram Conforms to the characteristic peak of R.S. | Conforms |
| Residue on ignition | Not more than 0.1% | 0.07% |
| Loss on drying | Not more than 0.5% | 0.38% |
| Heavy Metals | Not more than 20 ppm | Conforms |
| Single impurity | Not more than 0.15% | 0.13% |
| Total impurities | Not more than 1.0% | 0.56% |
| Purity[HPLC] | Not less than 99.0% | 99.44% |
| Assay(caculated on anhydrous basis) | 98.5%~101.5% | 99.3% |
SNC was established in 2006. After years of development, Good Fortune International joined the team in 2017 to jointly provide one-stop services for global users in the research and development, production, logistics, and sales of food, medicine, nutrition and health, and sports supplements.
The company has keen market observation and judgment, provides customers with the highest quality products and services with fast and sensitive response, and provides customers with "one-stop all-round" services! Committed to supplying healthy raw materials to the world, providing the highest quality raw materials for the world's health products, sports supplements, cosmetics, pharmaceuticals and other fields.
More Than 15 Years Experience
Our products are sold worldwide, like Europe, North&South America, Asia and pacific area as well as Africa, we are aiming to establish long term cooperation with our clients.
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Committed to supplying healthy raw materials to the world, providing the highest quality raw materials for the world's health products, sports supplements, cosmetics, pharmaceuticals and other fields. Customized product is also available from us.
7 DAYS 24 HOURS service
In time and clear response to customers questions. 100% guaranteed aftersales service, we are happy to provide guidance or solutions during your consumption.
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Dedicated to provide high-quality materials for customers with reasonable price.
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