Premium Water Soluble Mannitol Pellets for Bulking Agent

• Customization: Available
• Powder: No
• Customized: Non-Customized
• Model NO.: SNC00686
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Solid
• Purity: >99%
• Pallets: as Per Request
• Quality: Refined
• Appearance: Pellets
• CAS: 87-78-5
• Transport Package: 25kg/Carton
• Specification: Pharmaceutical Grade
• Trademark: SNC Good Fortune
• Origin: China
• HS Code: 29054300

Product Description

 

Product Description

 

Introduction:

Mannitol, a sugar alcohol, is widely used in pharmaceutical formulations and food products due to its unique physical and chemical properties. It is a stable crystalline non-hygroscopic solid, freely soluble in water (18.6% w/w at 20°C), and chemically inert. Being a non-reducing sugar alcohol, mannitol does not undergo Maillard reactions with amines, making it highly compatible with most drugs.
 

Functions:

1. Bulking Agent:
   • Freeze-Dried Injectable Products: Mannitol is commonly used as a bulking agent in freeze-dried injectable products. It increases the cake mass and prevents blowout during the freeze-drying process, resulting in a mechanically robust and pharmaceutically elegant lyophile.
   • Oral Dispersible and Chewable Tablets: Mannitol is the filler of choice for orally dispersible and chewable tablets due to its high solubility, pleasant taste, and mouthfeel. It provides a cool sensation when dissolved in the mouth and does not raise blood glucose levels or have a laxative effect.
2. Cryoprotector:
   • Freeze-Drying: Mannitol can be used as a cryoprotector in freeze-drying processes, helping to maintain the stability and integrity of biological molecules during the freezing and drying steps.
3. Drug Carrier:
   • Nasal and Pulmonary Delivery Systems: Mannitol is used as a drug carrier in nasal and pulmonary delivery systems, facilitating the penetration of drugs through biological barriers.
4. Tablet Formulation:
   • Direct Compression: Mannitol is available in various grades suitable for direct compression, providing good flowability and the ability to produce mechanically resistant tablets.
   • Wet Granulation: In wet granulation processes, mannitol improves the stability and properties of granules. It is partly solubilized by the granulation liquid and recrystallizes upon drying, enhancing the stability and consistency of the granules.

Application:

1. Pharmaceutical Formulations:
   • Tablets: Mannitol is used as a diluent in tablet formulations, particularly in orally disintegrating tablets (ODTs) and chewable tablets. Its non-hygroscopic nature and brittle fracture during compression make it ideal for these applications.
   • Injectables: Mannitol is added to many liquid injectable formulations to modify osmolarity and is used therapeutically as a diuretic and to reduce intracranial pressure.
2. Food Products:
   • Confectionery: Mannitol is used in confectionery products due to its sweet taste and low hygroscopicity, providing a pleasant mouthfeel and extended shelf life.
3. Medical Devices:
   • Dry Powder Inhalers: Mannitol is approved in the EU as a dry powder formulation for the add-on therapy in adult cystic fibrosis patients (Bronchitol®). Its osmotic effect changes the viscoelastic properties of mucus, increasing liquid content and thus improving mucociliary clearance.

 

Detailed Photos

 

 

Product Parameters

Item	Standard
Appearance	White crystalline powder
Assay (%)	98.0-102.0
Loss on drying (%)	≤0.5
Specific rotation	+23~+25°
Heavy metal (Pb) (%)	<10ppm
Arsenic (%)	≤0.0002
Nickel (%)	≤ 0.30
Oxalate (%)	<0.02
Sulfate (SO4) (%)	≤0.01
Chloride (Cl) (%)	≤0.003
Melting point ( ºC)	166-170 °C
Acidity	Conform
Residue on ignition (%)	<0.1
Storage	in the shade
Packing	25kg/bag

 

Other Advantaged Products

Vitamin A	Vitamin C
Vitamin B3	Vitamin D2
Vitamin B7	Vitamin D3
Vitamin B6	Vitamin K2
Vitamin B12	Vitamin B2
Vitamin B1	D-alpha Tocopheryl Acetate
Vitamin B4	Vitamin E
Vitamin B9	Nicotinamide

Chitosan	Inositol
Creatine Monohydrate	AAKG
L-Carnitine Base	Chondroitin Sulfate
L-Carnitine Fumarate	L-Carnitine HCL
Sodium Hyaluronate	L-Carnitine L-Tartrate
L-Carnitine	Lactoferrin
N-Acetyl-D-Glucosamine	Whey Protein
Protein Energy Bar	Coenzyme Q10

Ashwagandha Extract	Grape Seed Extract
Boswellia Serrata Extract	Grapefruit Extract
Cactus Extract	Green Coffee Bean Extract
Cranberry Extract	Green Tea Extract
Dandelion Extract	Maca Extract
Fenugreek Extract	Milk Thistle Extract
Garcinia Cambogia Extract	Olive Leaf Extract
Ginger Extract	Rhodiola Rosea Extract
Ginkgo Biloba Extract	Stevia Extract
Ginseng Root Extract	Tribulus Terrestris Extract
Ginkgo Biloba Extract	Turmeric Root Extract
Ginseng Root Extract	Wolfberry Extract

Pea Protein	Vital Wheat Protein
Almond Protein	Corn Protein
Rice Protein	Egg White Protein
Whey Protein	Collagen Protein
Hemp Hearts Protein	Fava Bean Protein
Soy Protein	Soy Protein Isolate
Yeast Protein	Hemp Protein
Mung Bean Protein	Pumpkin Protein
Chickpea Protein	Sunflower Protein

 

Erythritol	Sucralose
Stevia	Xylitol
Allulose	Maltitol
Aspartame	Lactitol
Dextrose Anhydrous	Rice Syrup
Dextrose Monohydrate	Polyflora Honey
Maltodextrin	Raffinose Pentahydrate
Monk Fruit Sweeteners	Fructose

 

Certifications

 

Company Profile

 

SNC TEAMS

VITAFOODS EXHIBITIONS

 

 

SNC was established in 2006. After years of development, Good Fortune International joined the team in 2017 to jointly provide one-stop services for global users in the research and development, production, logistics, and sales of food, medicine, nutrition and health, and sports supplements. 

The company has keen market observation and judgment, provides customers with the highest quality products and services with fast and sensitive response, and provides customers with "one-stop all-round" services! Committed to supplying healthy raw materials to the world, providing the highest quality raw materials for the world's health products, sports supplements, cosmetics, pharmaceuticals and other fields.
 

Our Advantages

 

1 - More Than 15 Years Experience	2 - One-Stop Service	3 - Days 24 Hours Service	4 - Quality Assurance
Our products are sold worldwide, like Europe, North&South America, Asia and pacific area as well as Africa, we are aiming to establish long term cooperation with our clients.	Committed to supplying healthy raw materials to the world, providing the highest quality raw materials for the world's health products, sports supplements, cosmetics, pharmaceuticals and other fields. Customized product is also available from us.	In time and clear response to customers questions. 100% guaranteed aftersales service, we are happy to provide guidance or solutions during your consumption.	Dedicated to provide high-quality materials for customers with reasonable price.